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本文研究了大孔吸附树脂提取喜树碱的方法，包括树脂的筛选，喜树碱溶液的浓度、温度、ｐＨ值和盐离子浓度对吸附的影响；解吸剂的选择，解吸剂的ｐＨ值、流速对解吸的影响。确定了适宜的吸附和解吸条件。
Abstract：Separation of camptothecin by adsorption with macroporous resin was investigated.The macroporous resin AB-8 was chosen as the adsorbent.The effects of pH, temperature,concentration of salt ion or camptothecin solution on adsorption and the effects of pH and flow rate of eluent on desorption were studied.This method was used to separate camptothecin from the fruit of camptotheca on a laboratory-scale and was found to give a satisfactory results.
［1］Becker，Y．；Olshevsky，U．；Int．J．Med．Sci．1973，9，1078［2］中国医学科学院上海药物研究所，中华医学杂志．1978，58，598［3］Wall，M．E．；Wani，M．C．；Cook，C．E．；Palmer，K．H．；J．Am．Chem．Soc．1966，88，33［4］林隆泽，赵志远，徐任生，化学学报，1977，35（3，4），227［5］湖北省药品标准，喜树碱，1980
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中图分类号:R284.2
引用信息:
[1]张红，童明容，潘继伦，俞耀庭，王永耀，黄杏林，黄加斗，胡雄军.大孔吸附树脂提取喜树碱的研究[J].离子交换与吸附,1995(02).
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